F-1

Name: F-1
SKU: A19269
Price: 420 CNY
Rating: 5 (288 reviews)

目录号: A19269

ALK and ROS1 dual inhibitor

F-1 是一种强效的 ALK 和 ROS1 双重抑制剂，能够抑制磷酸化 ALK 及其相关的下游信号通路，对 ALKWT、ROS1WT、ALKL1196M 和 ALKG1202R 的半抑制浓度（IC50）分别为 2.1 nM、2.3 nM、1.3 nM 和 3.9 nM。

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Grouped product items
规格	价格	库存
1mg	¥420.00	现货
5mg	¥945.00	现货
10mg	¥1,330.00	现货
25mg	¥2,275.00	现货
50mg	¥3,255.00	现货
100mg	¥4,515.00	现货
200mg	¥6,160.00	现货
*10mM 1mL in DMSO**	¥1,190.00	现货
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Data Sheet

SDS

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生物活性

Discription

F-1 is a potent ALK and ROS1 dual inhibitor, suppresses phospho-ALK and its relative downstream signaling pathways, with IC50s of 2.1 nM, 2.3 nM, 1.3 nM and 3.9 nM for ALKWT, ROS1WT, ALKL1196M and ALKG1202R, respectively.

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A19269
分子式	C22H27ClN8O3S
分子量	519.02
CAS号	2244775-31-1
SMILES	O=S(NC1=C(NC2=NC(NC3=C(OC)N=C(N4CCN(C)CC4)C=C3)=NC=C2Cl)C=CC=C1)(C)=O
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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