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Falcarindiol (FAD, (3R,8S)-Falcarindiol, FaDOH) is a natural polyacetylene compound found rich in many plants of the Umbelliferae family. Falcarindiol suppresses LPS-stimulated expression of inducible nitric oxide synthase (iNOS), tumor necrosis factor alpha (TNFα), interleukin-6 (IL-6), and interleukin-1 beta (IL-1β). Falcarindiol attenuates the LPS-induced activation of JNK, ERK, STAT1, and STAT3 signaling molecules. Falnidamol is a pyrimido-pyrimidine compound with anti-cancer activity.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 38.41 mL | 192.03 mL | 384.07 mL |
| 0.5 mM | 7.68 mL | 38.41 mL | 76.81 mL |
| 1 mM | 3.84 mL | 19.2 mL | 38.41 mL |
| 5 mM | 0.77 mL | 3.84 mL | 7.68 mL |
*The above data is based on the productmolecular weight 260.37. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A15623 |
|---|---|
| M. Wt | 260.37 |
| Formula | C17H24O2 |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 2 years |
| CAS No. | 225110-25-8 |
| SMILES | CCCCCCCC=CC(C#CC#CC(C=C)O)O |
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