Fatty acid synthase (FASN)
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FASN 抑制剂
C75是新型有效的脂肪酸合酶抑制剂(FAS),可作为研究代谢紊乱和癌症中脂肪酸合成的工具。
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FASN 抑制剂
C 75是脂肪酸合酶(FAS)的抑制剂,可减少小鼠的食物摄入量和体重。
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FASN inhibitor
TVB-3166 is an orally-available, reversible, potent, and selective FASN inhibitor, inducing apoptosis, inhibiting anchorage-independent cell growth under lipid-rich conditions, and inhibiting in-vivo xenograft tumor growth.
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FASN inhibitor
TVB-3664 is an orally available, reversible, potent, selective and highly bioavailable fatty acid synthase (FASN) inhibitor, with IC50 values of 18 nM and 12 nM for human and mouse cell palmitate synthesis, respectively. TVB-3664 significantly reduces tubulin palmitoylation and mRNA expression.
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FASN inhibitor
FASN-IN-2 is a Fatty Acid Synthase (FASN) inhibitor extracted from patent WO2012122391A1, compound 152, has an IC50 of 0.052 μM and an EC50 of 0.072 μM.
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FASN inhibitor
HS-80 is an enantiomer of Fasnall, which is a selective fatty acid synthase (FASN) inhibitor. HS-80 is able to inhibit the incorporation of tritiated acetate into lipids with an IC50 of 7.13 μM.
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