Filibuvir
目录号: A21392
non-nucleoside inhibitor
Filibuvir 是一种强效的、选择性的非核苷类抑制剂(NNI),针对 HCV 非结构蛋白 5B(NS5B)RNA 依赖性 RNA 聚合酶,并且它通过非共价方式结合在 NS5B 的 Thumb 2 口袋中。
Discription | Filibuvir is a potent, selective non-nucleoside inhibitor (NNI) of the HCV nonstructural 5B protein (NS5B) RNA-dependent RNA polymerase, and it binds noncovalently in the ??Thumb 2?? pocket of NS5B. | |||||
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Cell Research |
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目录号 | A21392 |
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分子式 | C29H37N5O3 |
分子量 | 503.64 |
CAS号 | 877130-28-4 |
SMILES | O=C(O1)C(CC2=NN(C(C)=C3)C(N=C3C)=N2)=C(O)C[C@@]1(C4CCCC4)CCC5=CC(CC)=NC(CC)=C5 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2