Fingolimod
目录号: A17798
S1P 拮抗剂
Fingolimod 是一种鞘氨醇1-磷酸(S1P)拮抗剂,在 K562 和 NK 细胞中的 IC50 为 0.033 nM。Fingolimod 还是一种 pak1 激活剂,具有免疫抑制作用。
Discription | Fingolimod is a sphingosine 1-phosphate (S1P) antagonist with IC50 of 0.033 nM in K562 and NK cells. Fingolimod also is a pak1 activator, a immunosuppressant. | |||||
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Targets |
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Cell Research |
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目录号 | A17798 |
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分子式 | C19H33NO2 |
分子量 | 307.48 |
CAS号 | 162359-55-9 |
SMILES | OCC(CCC1=CC=C(CCCCCCCC)C=C1)(N)CO |
其他名称 | Fingolimod; FTY720 (free base) |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 12 mg/mL (39.03 mM) | |
Water | Insoluble | ||
Ethanol | 5 mg/mL (16.26 mM) | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 32.52 mL | 162.61 mL | 325.22 mL |
0.5 mM | 6.5 mL | 32.52 mL | 65.04 mL |
1 mM | 3.25 mL | 16.26 mL | 32.52 mL |
5 mM | 0.65 mL | 3.25 mL | 6.5 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2