Fisogatinib

目录号: A20354
FGFR4 inhibitor
Fisogatinib(BLU-554)是一种强效、高度选择性且口服活性的成纤维细胞生长因子受体4(FGFR4)抑制剂,其IC50为5 nM。
Grouped product items
规格 价格 库存 数量
1mg
¥280.00
现货
5mg
¥805.00
现货
10mg
¥1,260.00
现货
25mg
¥2,240.00
现货
50mg
¥3,395.00
现货
100mg
¥5,180.00
现货
500mg
¥10,395.00
现货
10mM * 1mL in DMSO
¥910.00
现货
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重要通知:仅供研究使用。我们不向患者销售。

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生物活性
Discription Fisogatinib (BLU-554) is a potent, highly selective and orally active fibroblast growth factor receptor 4 (FGFR4) inhibitor with an IC50 of 5 nM.
Targets
Target Value
Cell Research
Cell Line Type Value Description References
产品信息
目录号 A20354
分子式 C24H24Cl2N4O4
分子量 503.38
CAS号 1707289-21-1
SMILES C=CC(N[C@@H]1[C@H](NC2=NC=C3C=C(C4=C(Cl)C(OC)=CC(OC)=C4Cl)C=CC3=N2)COCC1)=O
其他名称 BLU-554, BLU554, BLU 554
储存条件

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据
In vitro DMSO Warmed: 96 mg/mL (190.7 mM)
Water Insoluble
Ethanol Warmed: 2 mg/mL (3.97 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.87 mL 99.33 mL 198.66 mL
0.5 mM 3.97 mL 19.87 mL 39.73 mL
1 mM 1.99 mL 9.93 mL 19.87 mL
5 mM 0.4 mL 1.99 mL 3.97 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

  • Mass

    Concentration

    Volume

    Molecular Weight

Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

  • C1

    V1

    C2

    V2

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