Flavopiridol (Alvocidib)

Name: Flavopiridol (Alvocidib)
SKU: A10390
Price: 175 CNY
Rating: 5 (3 reviews)

目录号: A10390

CDK 抑制剂

3 篇发表文献

Flavopiridol（Alvocidib）是一种环依赖性激酶抑制剂，目前正在临床开发中，用于治疗慢性淋巴细胞性白血病。

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Grouped product items
规格	价格	库存
2mg	¥175.00	现货
5mg	¥245.00	现货
10mg	¥455.00	现货
25mg	¥805.00	现货
50mg	¥1,365.00	现货
100mg	¥2,520.00	现货
*10mM 1mL in DMSO**	¥637.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

Other Forms of Flavopiridol (Alvocidib)

Flavopiridol HCl

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用Flavopiridol (Alvocidib)发表的3篇文献

Reiko Watanabe, .et al. , J Med Chem, 2021, Mar 11;64(5):2725-2738 PMID: 33619967

Zhiyuan Zhao, .et al. , J Biol Chem, 2017, Sep 15; 292(37): 15489-15500 PMID: 28743741

Sami Kukkonen, .et al. , Retrovirology., 2014, 11: 30. PMID: 24742347

生物活性

Discription

Flavopiridol (Alvocidib) is a cyclin-dependent kinase inhibitor under clinical development for the treatment of chronic lymphocytic leukemia.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A10390
分子式	C21H20ClNO5
分子量	401.8
CAS号	146426-40-6
SMILES	CN1CC[C@@H]([C@@H](C1)O)C2=C(C=C(C3=C2OC(=CC3=O)C4=CC=CC=C4Cl)O)O
其他名称	HMR-1275, L868275
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	14 mg/mL (34.83 mM)
	Water	Insoluble
	Ethanol	7 mg/mL (17.41 mM)
In vivo	5% DMSO+30% PEG 300+ddH2O	2.3 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	24.89 mL	124.44 mL	248.88 mL
0.5 mM	4.98 mL	24.89 mL	49.78 mL
1 mM	2.49 mL	12.44 mL	24.89 mL
5 mM	0.5 mL	2.49 mL	4.98 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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