微信关注
Total item
Cart Subtotal
￥ 0.00 产品详情
Flavopiridol HCl是细胞周期蛋白依赖性激酶的抑制剂。（-）-顺式形式诱导特定肿瘤细胞的凋亡。
靶点信息
| CDK1 (Cell-free assay) | CDK2 (Cell-free assay) | CDK4 (Cell-free assay) | CDK6 (Cell-free assay) | CDK7 (Cell-free assay) |
| 40 nM | 40 nM | 40 nM | 40 nM | 300 nM |
| In vitro (25°C) | DMSO | 78 mg/mL (177.96 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
| In vivo | 2% DMSO+30% PEG 300+ddH2O | 4 mg/mL | |
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 22.82 mL | 114.08 mL | 228.15 mL |
| 0.5 mM | 4.56 mL | 22.82 mL | 45.63 mL |
| 1 mM | 2.28 mL | 11.41 mL | 22.82 mL |
| 5 mM | 0.46 mL | 2.28 mL | 4.56 mL |
*The above data is based on the productmolecular weight 438.3. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A11045 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 438.3 |
| Formula | C21H20ClNO5.HCl |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 131740-09-5 |
| SMILES | CN1CC[C@@H]([C@@H](C1)O)C2=C(C=C(C3=C2OC(=CC3=O)C4=CC=CC=C4Cl)O)O.Cl |
产品标签
Product Questions
Product Questions
No Questions
您还可能对下列产品感兴趣
AT7519 trifluoroacetate
AT7519 trifluoroacetate是CDK1、2、4、6和9的多CDK抑制剂，IC50为10-210 nM，对CDK3的效力较低，对CDK7的活性较低。
Flavopiridol (Alvocidib)
Flavopiridol（Alvocidib）是一种细胞周期蛋白依赖性激酶抑制剂，与ATP竞争性抑制CDK，包括CDK1， CDK2， CDK4和CDK…
JNJ-7706621
JNJ-7706621是对CDK1/2具有最高效力的pan-CDK抑制剂，IC50为9 nM/4 nM，并且在无细胞分析中对CDK1/2的选择性是CDK3/4/…
LEE011 (Ribociclib)
LEE011 (Ribociclib)是一种可口服的细胞周期蛋白依赖性激酶（CDK）抑制剂，靶向细胞周期蛋白D1/CDK4和细胞周期…
Purvalanol A
Purvalanol A是一种有效的细胞渗透性细胞周期蛋白依赖性蛋白激酶（cdk）抑制剂。对于cdc2/cyclin B，cdk2/cyclin A…
Keywords:购买 Flavopiridol HCl | Flavopiridol HCl 供应商 | 订购 Flavopiridol HCl | Flavopiridol HCl 价格 | Flavopiridol HCl 生产商 | 订单 Flavopiridol HCl | Flavopiridol HCl 代理商 | 购买 131740-09-5| 131740-09-5 供应商 | 订购 131740-09-5 | 131740-09-5 价格 | 131740-09-5 生产商 | 订单 131740-09-5 | 131740-09-5 代理商|buy Flavopiridol HCl | Flavopiridol HCl Supplier | purchase Flavopiridol HCl | Flavopiridol HCl cost | Flavopiridol HCl manufacturer | order Flavopiridol HCl | Flavopiridol HCl distributor | buy 131740-09-5| 131740-09-5 Supplier | purchase 131740-09-5 | 131740-09-5 cost | 131740-09-5 manufacturer | order 131740-09-5 | 131740-09-5 distributor