FLI-06

Name: FLI-06
SKU: A13815

目录号: A13815

Gamma-secretase 抑制剂

Product Citations (1)

FLI-06 Chemical Structure

CAS NO. 313967-18-9

FLI-06是一种Notch抑制剂和早期分泌途径抑制剂。FLI-06以不同于布雷菲德菌素A和杀真菌剂A的方式破坏高尔基体。

库存：现货

规格	价格	数量
10 mg	￥ 840.00
25 mg	￥ 1,575.00
50 mg	￥ 2,800.00
100 mg	￥ 4,900.00
10mM * 1mL in DMSO	￥ 910.00

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生物活性

FLI-06是一种Notch抑制剂和早期分泌途径抑制剂。FLI-06以不同于布雷菲德菌素A和杀真菌剂A的方式破坏高尔基体。

靶点信息

Notch
2.3 μM(EC50)

溶解度 *

In vitro	DMSO	80 mg/mL (182.43 mM)
	Water	Insoluble
	Ethanol	7 mg/mL (15.96 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	22.8 mL	114.02 mL	228.04 mL
0.5 mM	4.56 mL	22.8 mL	45.61 mL
1 mM	2.28 mL	11.4 mL	22.8 mL
5 mM	0.46 mL	2.28 mL	4.56 mL

*The above data is based on the productmolecular weight 438.52. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A13815
作用机制	Inhibitor (抑制剂)
M. Wt	438.52
Formula	C25H30N2O5
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	313967-18-9
Synonyms	FLI06,FLI 06
SMILES	CC1=C(C(C2=C(N1)CC(CC2=O)(C)C)C3=CC=C(C=C3)[N+](=O)[O-])C(=O)OC4CCCCC4