FLT3-IN-1
目录号: A16249
FLT3 抑制剂
FLT3-IN-1 是一种新型的高效选择性 Flt3 抑制剂,其对 Flt3 的 IC50 为 10 nM;针对表达 FLT3-ITD 的 MV4-11 细胞,IC50 为 6 nM。
Discription | FLT3-IN-1 is a novel potent and selective Flt3 inhibitor with IC50 of 10 nM; against FLT3-ITD-expressing MV4-11 cells with IC50 of 6 nM. | |||||
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Cell Research |
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目录号 | A16249 |
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分子式 | C25H27N7O3S2 |
分子量 | 537.66 |
CAS号 | 1370256-78-2 |
SMILES | CC1=CC=C(C=C1)NC(=O)NC2=NN=C(S2)SC3=NC=NC4=C3C=CC(=C4)OCCCN5CCOCC5 |
其他名称 | SKLB4771 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 43 mg/mL (79.97 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 18.6 mL | 93 mL | 185.99 mL |
0.5 mM | 3.72 mL | 18.6 mL | 37.2 mL |
1 mM | 1.86 mL | 9.3 mL | 18.6 mL |
5 mM | 0.37 mL | 1.86 mL | 3.72 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2