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Fludarabine (Fludara)

目录号: A10396
STAT 抑制剂
Fludarabine或fludarabine phosphate(Fludara)是一种用于治疗血液系统恶性肿瘤(如白血病和淋巴瘤等血细胞癌)的化疗药物。Fludarabine通过干扰核糖核苷酸还原酶和DNA聚合酶来抑制DNA合成。它对分裂中和静息状态的细胞均有效。
Grouped product items
规格 价格 库存 数量
5mg
¥210.00
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10mg
¥280.00
现货
25mg
¥525.00
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50mg
¥665.00
现货
100mg
¥945.00
现货
200mg
¥1,330.00
现货
10mM * 1mL in DMSO
¥315.00
现货
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重要通知:仅供研究使用。我们不向患者销售。

顾客使用 Adooq 产品发表的高质量科研文献
Adooq用户使用Fludarabine (Fludara)发表的1篇文献
  • Irene Dell'Anno, .et al. , Invest New Drugs, 2020, Dec 9 PMID: 33300108
  • 生物活性
    Discription Fludarabine or fludarabine phosphate (Fludara) is a chemotherapy drug used in the treatment of hematological malignancies (cancers of blood cells such as leukemias and lymphomas) .Fludarabine inhibits DNA synthesis by interfering with ribonucleotide reductase and DNA polymerase. It is active against both dividing and resting cells.
    Targets
    Target Value
    Cell Research
    Cell Line Type Value Description References
    产品信息
    目录号 A10396
    分子式 C10H12FN5O4
    分子量 285.2
    CAS号 21679-14-1
    SMILES C1=NC2=C(N=C(N=C2N1[C@H]3[C@H]([C@@H]([C@H](O3)CO)O)O)F)N
    其他名称 F-ara-A, NSC 118218
    储存条件

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    溶解性数据
    In vitro (25°C) DMSO 52 mg/mL (182.3 mM)
    Water Insoluble
    Ethanol Insoluble
    In vivo 30% propylene glycol, 5% Tween 80, 65% D5W 28 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 35.06 mL 175.32 mL 350.63 mL
    0.5 mM 7.01 mL 35.06 mL 70.13 mL
    1 mM 3.51 mL 17.53 mL 35.06 mL
    5 mM 0.7 mL 3.51 mL 7.01 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

    • Mass

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      Molecular Weight

    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

    • C1

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