Flumequine

Name: Flumequine
SKU: A11861

目录号: A11861

Topoisomerase II 抑制剂

Flumequine Chemical Structure

CAS NO. 42835-25-6

Flumequine是一种合成化学抗生素，可在回旋酶/拓扑异构酶水平上影响哺乳动物染色体和DNA的解链。抑制拓扑异构酶II， IC50为15 μM。

库存：现货

规格	价格	数量
100 mg	￥ 350.00
500 mg	￥ 1,050.00

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生物活性

Flumequine是一种合成化学抗生素，可在回旋酶/拓扑异构酶水平上影响哺乳动物染色体和DNA的解链。抑制拓扑异构酶II， IC50为15 μM。

靶点信息

Topo II
15 μM

溶解度 *

In vitro	DMSO	3 mg/mL (11.48 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	38.28 mL	191.39 mL	382.78 mL
0.5 mM	7.66 mL	38.28 mL	76.56 mL
1 mM	3.83 mL	19.14 mL	38.28 mL
5 mM	0.77 mL	3.83 mL	7.66 mL

*The above data is based on the productmolecular weight 261.25. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A11861
作用机制	Inhibitor (抑制剂)
M. Wt	261.25
Formula	C14H12FNO3
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	42835-25-6
SMILES	CC1CCC2=C3N1C=C(C(=O)C3=CC(=C2)F)C(=O)O