Flurizan

Name: Flurizan
SKU: A12433
Price: 315 CNY
Rating: 5 (288 reviews)

目录号: A12433

gamma-secretase modulator

Flurizan 是一种非甾体抗炎药（NSAID），它抑制 γ-分泌酶 活性。

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规格	价格	库存
100mg	¥315.00	现货
250mg	¥735.00	现货
500mg	¥1,365.00	现货
1g	¥2,415.00	现货
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Data Sheet

SDS

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生物活性

Discription

Flurizan is a nonsteroidal anti-inflammatory drug (NSAID) that inhibits γ-secretase activity.

Cell Research

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Cell Line	Type	Value	Description	References
CHO	EC50	300 μM	Modulation of gamma-secretase expressed in CHO cells co-expressing polyhistidine-tagged APP695NL I-his with FAD-linked Swedish and London mutation assessed as reduction in amyloid beta42 production after 2 hrs by ELISA	[PMID: 22061640]
CHO	IC50	305 μM	Modulation of gamma-secretase-mediated cleavage of human APP expressed in CHO cells with human presenilin-1 assessed as inhibition of amyloid beta42 production after 24 hrs by ELISA	[PMID: 20503989]

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产品信息

目录号	A12433
分子式	C15H13FO2
分子量	244.26
CAS号	51543-40-9
SMILES	C[C@H](C1=CC(=C(C=C1)C2=CC=CC=C2)F)C(=O)O
其他名称	(R)-Flurbiprofen, MPC 7869, MPC-7869, MPC7869, Tarenflurbil
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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