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Foliglurax monohydrochloride (PXT002331 monohydrochloride) is a highly selective and potent, brain-penetrant metabotropic glutamate receptor 4 positive allosteric modulator (mGluR4 PAM) , with an EC50 of 79 nM. Antiparkinsonian effect.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 21.84 mL | 109.18 mL | 218.35 mL |
| 0.5 mM | 4.37 mL | 21.84 mL | 43.67 mL |
| 1 mM | 2.18 mL | 10.92 mL | 21.84 mL |
| 5 mM | 0.44 mL | 2.18 mL | 4.37 mL |
*The above data is based on the productmolecular weight 457.97. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A21384 |
|---|---|
| 作用机制 | Modulator (调节剂) |
| M. Wt | 457.97 |
| Formula | C23H24ClN3O3S |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 2133294-96-7 |
| Synonyms | PXT002331 (monohydrochloride), PXT 002331, PXT-002331 |
| SMILES | O/N=C1C=C(C2=CC3=C(C=CS3)C=N2)OC4=CC=C(CCCN5CCOCC5)C=C\14.Cl |
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