Fosamprenavir Calcium Salt
目录号: A15089
HIV protease 抑制剂
Fosamprenavir Calcium Salt 是一种抗逆转录病毒蛋白酶抑制剂安普仑韦的磷酸酯前体药物,相比原始分子具有更好的溶解性,并且在当前的给药方案中有可能减少药丸负担;GW433908G 是该前体药物的钙盐。
Discription | Fosamprenavir Calcium Salt is a phosphate ester prodrug of the antiretroviral protease inhibitor amprenavir, with improved solubility over the parent molecule and a potential for reduced pill burden on current dosing regimens; GW433908G is the calcium salt of the prodrug. |
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目录号 | A15089 |
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分子式 | C25H34CaN3O9PS |
分子量 | 623.67 |
CAS号 | 226700-81-8 |
SMILES | CC(C)CN(CC(C(CC1=CC=CC=C1)NC(=O)OC2CCOC2)OP(=O)([O-])[O-])S(=O)(=O)C3=CC=C(C=C3)N.[Ca+2] |
其他名称 | GW 433908G, Lexiva, GW433908G, GW-433908G |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 93 mg/mL (149.12 mM) | |
Water | Insoluble | ||
Ethanol | 3 mg/mL (4.81 mM) | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 16.03 mL | 80.17 mL | 160.34 mL |
0.5 mM | 3.21 mL | 16.03 mL | 32.07 mL |
1 mM | 1.6 mL | 8.02 mL | 16.03 mL |
5 mM | 0.32 mL | 1.6 mL | 3.21 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2