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FR 180204

FR 180204

Name: FR 180204
SKU: A14119

目录号: A14119

ERK 抑制剂

Product Citations (2)

FR 180204 Chemical Structure

CAS NO. 865362-74-9

FR 180204是细胞外信号调节激酶（ERK）的新型选择性抑制剂，它可能是类风湿关节炎的潜在新疗法。

库存：现货

规格	价格	数量
10 mg	￥ 840.00
25 mg	￥ 1,750.00
50 mg	￥ 2,800.00
10mM * 1mL in DMSO	￥ 665.00

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生物活性

FR 180204是细胞外信号调节激酶（ERK）的新型选择性抑制剂，它可能是类风湿关节炎的潜在新疗法。

靶点信息

ERK2	ERK1
0.14 μM(Ki)	0.31 μM(Ki)

溶解度 *

In vitro	DMSO	57 mg/mL (174.13 mM)
	Water	Insoluble
	Ethanol	Warmed: 2 mg/mL (6.1 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	30.55 mL	152.75 mL	305.49 mL
0.5 mM	6.11 mL	30.55 mL	61.1 mL
1 mM	3.05 mL	15.27 mL	30.55 mL
5 mM	0.61 mL	3.05 mL	6.11 mL

*The above data is based on the productmolecular weight 327.34. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A14119
作用机制	Inhibitor (抑制剂)
M. Wt	327.34
Formula	C18H13N7
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	865362-74-9
Synonyms	FR-180204,FR180204
SMILES	C1=CC=C(C=C1)C2=NN3C=CC=CC3=C2C4=CC5=C(NN=C5N=N4)N