FRAX1036
目录号: A16557
PAK 抑制剂
FRAX1036 是一种PAK抑制剂，其Kis分别为PAK1为23.3 nM、PAK2为72.4 nM、PAK4为2.4 μM。
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生物活性
| Discription | FRAX1036 is a PAK inhibitor with Kis of 23.3 nM, 72.4 nM, and 2.4 μM for PAK1, PAK2 and PAK4, respectively. | ||
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产品信息
| 目录号 | A16557 |
|---|---|
| 分子式 | C28H32ClN7O |
| 分子量 | 518.05 |
| CAS号 | 1432908-05-8 |
| SMILES | O=C1C(C2=CC=C(C3=NC(C)=CN=C3)C=C2Cl)=CC4=CN=C(NCCC5CCN(C)CC5)N=C4N1CC |
| 其他名称 | FRAX-1036, FRAX 1036 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | Insoluble | |
| Water | Insoluble | ||
| Ethanol | 17 mg/mL (32.81 mM) | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 19.3 mL | 96.52 mL | 193.03 mL |
| 0.5 mM | 3.86 mL | 19.3 mL | 38.61 mL |
| 1 mM | 1.93 mL | 9.65 mL | 19.3 mL |
| 5 mM | 0.39 mL | 1.93 mL | 3.86 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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| 购买 1432908-05-8 | 1432908-05-8 供应商 | 1432908-05-8 花费 | 1432908-05-8 生产商 | 订购 1432908-05-8 | 1432908-05-8 代理商