FT113
目录号: A19402
FASN inhibitor
FT113 是一种强效且可口服的脂肪酸合酶（FASN）抑制剂，对全长重组人类FASN酶的IC50为213 nM。
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生物活性
| Discription | FT113 is a potent and orally active fatty acid synthase (FASN) inhibitor, with an IC50 of 213 nM for full-length recombinant human FASN enzyme. | |||||
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产品信息
| 目录号 | A19402 |
|---|---|
| 分子式 | C22H20FN3O4 |
| 分子量 | 409.41 |
| CAS号 | 1630808-89-7 |
| SMILES | O=C(C1(CC1)O)N2CCN(C(C3=CC=C(C4=NC5=C(C=C(F)C=C5)O4)C=C3)=O)CC2 |
| 其他名称 | FT 113, FT-113 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | 25 mg/mL (61.06 mM) | |
| Water | Insoluble | ||
| Ethanol | 3 mg/mL (7.32 mM) | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 24.43 mL | 122.13 mL | 244.25 mL |
| 0.5 mM | 4.89 mL | 24.43 mL | 48.85 mL |
| 1 mM | 2.44 mL | 12.21 mL | 24.43 mL |
| 5 mM | 0.49 mL | 2.44 mL | 4.89 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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