Fumagillin
目录号: A15299
Aminopeptidase 抑制剂
Fumagillin 是一种复杂的天然产物抗生素，它与蛋氨酸氨肽酶II型（MetAP-2）的关键组氨酸残基形成共价键，从而抑制内皮细胞增殖和血管生成。
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生物活性
| Discription | Fumagillin is a complex natural product antibiotic which covalently binds a key histidine residue of methionine aminopeptidase type II (MetAP-2), inhibiting endothelial cell proliferation and angiogenesis. | |||||
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产品信息
| 目录号 | A15299 |
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| 分子式 | C26H34O7 |
| 分子量 | 458.55 |
| CAS号 | 23110-15-8 |
| SMILES | CC(=CCC1C(O1)(C)C2C(C(CCC23CO3)OC(=O)C=CC=CC=CC=CC(=O)O)OC)C |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | 86 mg/mL (187.55 mM) | |
| Water | Insoluble | ||
| Ethanol | Warmed: 30 mg/mL (65.42 mM) | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 21.81 mL | 109.04 mL | 218.08 mL |
| 0.5 mM | 4.36 mL | 21.81 mL | 43.62 mL |
| 1 mM | 2.18 mL | 10.9 mL | 21.81 mL |
| 5 mM | 0.44 mL | 2.18 mL | 4.36 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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| 购买 23110-15-8 | 23110-15-8 供应商 | 23110-15-8 花费 | 23110-15-8 生产商 | 订购 23110-15-8 | 23110-15-8 代理商