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Fumarate hydratase-IN-1 (compound 2) is a cell-permeable fumarate hydratase inhibitor. Fumarate hydratase-IN-1 has antiproliferative activity against several cancer cell lines with a mean IC50 of 2.2 μM.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 22.39 mL | 111.97 mL | 223.94 mL |
| 0.5 mM | 4.48 mL | 22.39 mL | 44.79 mL |
| 1 mM | 2.24 mL | 11.2 mL | 22.39 mL |
| 5 mM | 0.45 mL | 2.24 mL | 4.48 mL |
*The above data is based on the productmolecular weight 446.54. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A20471 |
|---|---|
| M. Wt | 446.54 |
| Formula | C27H30N2O4 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 1644060-37-6 |
| SMILES | O=C(OCC)[C@]1([C@H](CC(NC)=O)C2=O)C(N2CC(C=C3)=CC=C3C4=CC=CC=C4)=CCCC1 |
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