Ganetespib (STA-9090)

Name: Ganetespib (STA-9090)
SKU: A11402
Price: 385 CNY
Rating: 5 (7 reviews)

目录号: A11402

Hsp90 抑制剂

7 篇发表文献

Ganetespib 是一种强效的合成小分子抑制剂，针对 Hsp90，这是一种对某些促进多种不同类型癌症的生长、增殖和存活的蛋白质的功能至关重要的伴侣蛋白。

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Grouped product items
规格	价格	库存
5mg	¥385.00	现货
10mg	¥560.00	现货
25mg	¥910.00	现货
50mg	¥1,120.00	现货
100mg	¥1,785.00	现货
200mg	¥3,080.00	现货
500mg	¥5,110.00	现货
*10mM 1mL in DMSO**	¥420.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用Ganetespib (STA-9090)发表的7篇文献

Dilay Karademir, .et al. , Med Oncol, 2023, Jul 11;40(8):234 PMID: 37432531

Tung-Yun Wu, .et al. , J Adv Res, 2022, Jun 22;S2090-1232(22)00148-5 PMID: 35752438

Aykut Ozgur, .et al. , J Chemother, 2021, Apr 2;1-10 PMID: 33794753

Michael Heider, .et al. , Mol Cell, 2021, Mar 18;81(6):1170-1186 PMID: 33571422

Kosinsky RL, .et al. , Cell Death Dis, 2019, Dec 4;10(12):911 PMID: 31801945

Yamada-Kanazawa S, .et al. , Br J Dermatol, 2017, Aug;177(2):456-469 PMID: 28078663

Hiroki Murano, .et al. , Plant Biotechnol Rep, 2017, 11:107-113

生物活性

Discription

Ganetespib is a potent, synthetic, small molecule inhibitor of Hsp90, a chaperone protein that is essential to the function of certain other proteins that drive the growth, proliferation, and survival of many different types of cancer.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A11402
分子式	C20H20N4O3
分子量	364.4
CAS号	888216-25-9
SMILES	CC(C)C1=CC(=C2NNC(=O)N2C3=CC4=C(C=C3)N(C=C4)C)C(=O)C=C1O
其他名称	STA9090
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	37 mg/mL (101.53 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	5% DMSO+45% PEG 300+ddH2O	10 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	27.44 mL	137.21 mL	274.42 mL
0.5 mM	5.49 mL	27.44 mL	54.88 mL
1 mM	2.74 mL	13.72 mL	27.44 mL
5 mM	0.55 mL	2.74 mL	5.49 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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