产品详情
Ganetespib (STA-9090)是Hsp90的有效合成小分子抑制剂,Hsp90是一种伴侣蛋白,对于某些其他蛋白的功能至关重要,这些蛋白可驱动许多不同类型的癌症的生长,增殖和存活。
靶点信息
HSP90 (OSA 8 cells) | ||||
4 nM |
In vitro (25°C) | DMSO | 37 mg/mL (101.53 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
In vivo | 5% DMSO+45% PEG 300+ddH2O | 10 mg/mL | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 27.44 mL | 137.21 mL | 274.42 mL |
0.5 mM | 5.49 mL | 27.44 mL | 54.88 mL |
1 mM | 2.74 mL | 13.72 mL | 27.44 mL |
5 mM | 0.55 mL | 2.74 mL | 5.49 mL |
*The above data is based on the productmolecular weight 364.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
目录号 | A11402 |
---|---|
作用机制 | Inhibitor (抑制剂) |
M. Wt | 364.4 |
Formula | C20H20N4O3 |
Purity | >99% |
Storage | Store lyophilized at -20ºC, keep desiccated. |
CAS No. | 888216-25-9 |
Synonyms | STA9090 |
SMILES | CC(C)C1=CC(=C2NNC(=O)N2C3=CC4=C(C=C3)N(C=C4)C)C(=O)C=C1O |
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