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藤黄酚是从印度藤黄中分离的聚异戊二烯基二苯甲酮衍生物。 在体外和体内，它都是有效的组蛋白乙酰转移酶（HATs）p300（IC50 = 7?M）和PCAF（IC50 = 5?M）抑制剂。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 16.59 mL | 82.95 mL | 165.89 mL |
| 0.5 mM | 3.32 mL | 16.59 mL | 33.18 mL |
| 1 mM | 1.66 mL | 8.29 mL | 16.59 mL |
| 5 mM | 0.33 mL | 1.66 mL | 3.32 mL |
*The above data is based on the productmolecular weight 602.8. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A12814 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 602.8 |
| Formula | C38H50O6 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 78824-30-3 |
| Synonyms | camboginol |
| SMILES | CC(=CC[C@@H]1C[C@@]2(C(=O)/C(=C(\C3=CC(=C(C=C3)O)O)/O)/C(=O)[C@@](C2=O)(C1(C)C)CC=C(C)C)C[C@H](CC=C(C)C)C(=C)C)C |
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