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GB-88 is a novel selective, orally available PAR2 antagonist, inhibits PAR2 activated Ca2+ release with an IC50 of 2 ?M.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 18.29 mL | 91.46 mL | 182.91 mL |
| 0.5 mM | 3.66 mL | 18.29 mL | 36.58 mL |
| 1 mM | 1.83 mL | 9.15 mL | 18.29 mL |
| 5 mM | 0.37 mL | 1.83 mL | 3.66 mL |
*The above data is based on the productmolecular weight 546.71. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A18779 |
|---|---|
| 作用机制 | Antagonist (拮抗剂) |
| M. Wt | 546.71 |
| Formula | C32H42N4O4 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 1416435-96-5 |
| Synonyms | GB88, GB 88 |
| SMILES | O=C(C1=CC=NO1)N[C@@H](CC2CCCCC2)C(N[C@@H]([C@@H](C)CC)C(N3CCC4(CC3)C=CC5=C4C=CC=C5)=O)=O |
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