GB1107
GB1107 是一种强效、选择性、口服活性的Galectin-3 (Gal-3)抑制剂,对人类Galectin-3的Kd为37 nM。GB1107能减少人类和小鼠肺腺癌的生长,并在同种模型中阻断转移。
Discription | GB1107 is a potent, selective, orally active inhibitor of Galectin-3 (Gal-3) with a Kd of 37 nM for human Galectin-3. GB1107 reduces human and mouse lung adenocarcinoma growth and blocks metastasis in the syngeneic model. |
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目录号 | A18591 |
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分子式 | C20H16Cl2F3N3O4S |
分子量 | 522.32 |
CAS号 | 1978336-61-6 |
SMILES | O[C@H]([C@@H](N1N=NC(C2=CC(F)=C(F)C(F)=C2)=C1)[C@H]([C@@H](CO)O3)O)[C@H]3SC4=CC=C(Cl)C(Cl)=C4 |
其他名称 | GB 1107, GB-1107 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2