GCN2iB
目录号: A19806
GCN2 inhibitor
GCN2iB 是一种针对丝氨酸/苏氨酸蛋白激酶 广义控制非抑制因子2(GCN2)的 ATP竞争性抑制剂,其 IC50 为2.4 nM。
Discription | GCN2iB is an ATP-competitive inhibitor of a serine/threonine-protein kinase general control nonderepressible 2 (GCN2), with an IC50 of 2.4 nM. |
---|
目录号 | A19806 |
---|---|
分子式 | C18H12ClF2N5O3S |
分子量 | 451.83 |
CAS号 | 2183470-12-2 |
SMILES | O=S(C1=CC(Cl)=CN=C1OC)(NC2=CC=C(F)C(C#CC3=CN=C(N)N=C3)=C2F)=O |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 13 mg/mL (28.76 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 22.13 mL | 110.66 mL | 221.32 mL |
0.5 mM | 4.43 mL | 22.13 mL | 44.26 mL |
1 mM | 2.21 mL | 11.07 mL | 22.13 mL |
5 mM | 0.44 mL | 2.21 mL | 4.43 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2