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GDC-0339

目录号: A20920
Pim kinase 抑制剂
GDC-0339 是一种效力强大、口服生物利用度高且耐受性良好的全面 Pim激酶抑制剂,其对Pim1、Pim2和Pim3的Kis分别为0.03 nM、0.1 nM和0.02 nM。GDC-0339 被发现作为多发性骨髓瘤的潜在治疗药物。
Grouped product items
规格 价格 库存 数量
2mg
¥1,925.00
现货
5mg
¥3,115.00
现货
10mg
¥5,215.00
现货
25mg
¥11,515.00
现货
50mg
¥15,015.00
现货
100mg
¥26,075.00
现货
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重要通知:仅供研究使用。我们不向患者销售。

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生物活性
Discription GDC-0339 is a potent, orally bioavailable and well tolerated pan-Pim kinase inhibitor, with Kis of 0.03 nM, 0.1 nM and 0.02 nM for Pim1, Pim2 and Pim3, respectively. GDC-0339 is discovered as a potential treatment of multiple myeloma.
Cell Research
Cell Line Type Value Description References
产品信息
目录号 A20920
分子式 C20H22F3N7OS
分子量 465.5
CAS号 1428569-85-0
SMILES FC1=CC=CC(F)=C1C2=NC(C(NC3=C(N4CC[C@@H](F)[C@H](N)CC4)N(C)N=C3)=O)=C(N)S2
其他名称 GDC0339, GDC 0339
储存条件

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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    C2

    V2

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