主页 /
Cell Cycle /
Chk /
GDC-0575 dihydrochloride

GDC-0575 dihydrochloride

Name: GDC-0575 dihydrochloride
SKU: A21567

目录号: A21567

CHK1 inhibitor

GDC-0575 dihydrochloride Chemical Structure

CAS NO. 1657014-42-0

GDC-0575 dihydrochloride (ARRY-575 dihydrochloride) is an orally bioavailable CHK1 inhibitor, with an IC50 of 1.2 nM, and has antitumor activity.

库存：现货

规格	价格	数量
5 mg	￥ 1,323.00
10 mg	￥ 2,282.00
50 mg	￥ 6,762.00
100 mg	￥ 13,524.00

大包装询价

或

添加到收藏

产品仅用于科学研究，不针对患者销售，望谅解.

产品详情

生物活性

GDC-0575 dihydrochloride (ARRY-575 dihydrochloride) is an orally bioavailable CHK1 inhibitor, with an IC50 of 1.2 nM, and has antitumor activity.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	22.16 mL	110.82 mL	221.64 mL
0.5 mM	4.43 mL	22.16 mL	44.33 mL
1 mM	2.22 mL	11.08 mL	22.16 mL
5 mM	0.44 mL	2.22 mL	4.43 mL

*The above data is based on the productmolecular weight 451.19. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A21567
作用机制	Inhibitor (抑制剂)
M. Wt	451.19
Formula	C16H22BrCl2N5O
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	1657014-42-0
Synonyms	ARRY-575 dihydrochloride, ARRY575, ARRY 575; RG7741 dihydrochloride, RG 7741, RG-7741, GDC0575, GDC 0575
SMILES	O=C(C1CC1)NC2=CNC3=C2C(N4C[C@H](N)CCC4)=C(Br)C=C3.[H]Cl.[H]Cl