顾客使用 Adooq 产品发表的高质量科研文献
Adooq用户使用GDC-0879发表的1篇文献
生物活性
| Discription | GDC-0879 is a specific inhibitor of B-Raf kinase enzyme,targeting B-Raf (V600E) (IC50: 0.13 nM). | |||||
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| Cell Research |
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产品信息
| 目录号 | A10420 |
|---|---|
| 分子式 | C19H18N4O2 |
| 分子量 | 334.4 |
| CAS号 | 905281-76-7 |
| SMILES | C1C/C(=N\O)/C2=C1C=C(C=C2)C3=CN(N=C3C4=CC=NC=C4)CCO |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro (25°C) | DMSO | Warmed: 65 mg/mL (194.39 mM) | |
| Water | Insoluble | ||
| Ethanol | 5 mg/mL (14.95 mM) | ||
| In vivo | 0.5% methylcellulose+0.2% Tween 80 | 28 mg/mL | |
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 29.9 mL | 149.52 mL | 299.04 mL |
| 0.5 mM | 5.98 mL | 29.9 mL | 59.81 mL |
| 1 mM | 2.99 mL | 14.95 mL | 29.9 mL |
| 5 mM | 0.6 mL | 2.99 mL | 5.98 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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| 购买 905281-76-7 | 905281-76-7 供应商 | 905281-76-7 花费 | 905281-76-7 生产商 | 订购 905281-76-7 | 905281-76-7 代理商