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GDC046

目录号: A22299
TYK2 抑制剂
GDC046(化合物3)是一种强效、选择性且口服生物利用度高的TYK2抑制剂,其Ki值分别为4.8 nM(针对TYK2)、83.8 nM(针对JAK1)、27.6 nM(针对JAK2)和253 nM(针对JAK3)。
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规格 价格 库存 数量
1mg
¥245.00
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5mg
¥665.00
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10mg
¥1,120.00
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25mg
¥2,170.00
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50mg
¥3,360.00
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100mg
¥5,250.00
现货
200mg
¥6,860.00
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重要通知:仅供研究使用。我们不向患者销售。

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生物活性
Discription GDC046 (Compound 3) is a potent, selective, and orally bioavailable inhibitor of TYK2 with Ki of 4.8 nM, 83.8 nM, 27.6 nM and 253 nM for TYK2, JAK1, JAK2, and JAK3, respectively.
Cell Research
Cell Line Type Value Description References
产品信息
目录号 A22299
分子式 C16H13Cl2N3O2
分子量 350.2
CAS号 1258292-64-6
SMILES O=C(NC1=CC(NC(C2CC2)=O)=NC=C1)C3=C(Cl)C=CC=C3Cl
其他名称 GDC-046,GDC 046
储存条件

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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