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Gefitinib hydrochloride

目录号: A15093
EGFR 抑制剂
Gefitinib hydrochloride 是一种 EGFR 抑制剂,它通过阻断靶细胞中的表皮生长因子受体(EGFR)信号传导来发挥作用。因此,它只对具有突变和过度活跃的 EGFR 的癌症有效。
Grouped product items
规格 价格 库存 数量
500mg
¥280.00
现货
1g
¥490.00
现货
5g
¥1,260.00
现货
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重要通知:仅供研究使用。我们不向患者销售。

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生物活性
Discription Gefitinib hydrochloride is an EGFR inhibitor, which interrupts signaling through the epidermal growth factor receptor (EGFR) in target cells. Therefore, it is only effective in cancers with mutated and overactive EGFR.
Targets
Target Value
产品信息
目录号 A15093
分子式 C22H25Cl2FN4O3
分子量 483.36
CAS号 184475-55-6
SMILES COC1=C(C=C2C(=C1)N=CN=C2NC3=CC(=C(C=C3)F)Cl)OCCCN4CCOCC4.Cl
其他名称 Iressa hydrochloride, ZD 1839 hydrochloride, ZD-1839 hydrochloride, ZD1839 hydrochloride
储存条件

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据
In vitro DMSO 7 mg/mL (14.48 mM)
Water 1 mg/mL (2.06 mM)
Ethanol 1 mg/mL (2.06 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.69 mL 103.44 mL 206.89 mL
0.5 mM 4.14 mL 20.69 mL 41.38 mL
1 mM 2.07 mL 10.34 mL 20.69 mL
5 mM 0.41 mL 2.07 mL 4.14 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

  • Mass

    Concentration

    Volume

    Molecular Weight

Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

  • C1

    V1

    C2

    V2

  • Calculator Reset
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