Gefitinib (Iressa)

Name: Gefitinib (Iressa)
SKU: A10422
Price: 245 CNY
Rating: 5 (2 reviews)

目录号: A10422

EGFR 抑制剂

2 篇发表文献

Gefitinib 是一种 EGFR 抑制剂，它通过干扰靶细胞中的表皮生长因子受体（EGFR）信号传导。

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Grouped product items
规格	价格	库存
100mg	¥245.00	现货
250mg	¥315.00	现货
500mg	¥350.00	现货
1g	¥455.00	现货
5g	¥980.00	现货
*10mM 1mL in DMSO**	¥315.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

Other Forms of Gefitinib (Iressa)

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用Gefitinib (Iressa)发表的2篇文献

Hamzehlou S, .et al. , Eur J Pharmacol, 2019, Nov 15;863:172705 PMID: 31574259

Mansi Srivastava, .et al. , Int Immunopharmacol, 2019, 71: 188-197 PMID: 30909134

生物活性

Discription

Gefitinib is an EGFR inhibitor, which interrupts signaling through the epidermal growth factor receptor (EGFR) in target cells.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A10422
分子式	C22H24ClFN4O3
分子量	446.9
CAS号	184475-35-2
SMILES	COC1=C(C=C2C(=C1)N=CN=C2NC3=CC(=C(C=C3)F)Cl)OCCCN4CCOCC4
其他名称	ZD-1839
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	80 mg/mL (179 mM)
	Water	Insoluble
	Ethanol	4 mg/mL (8.95 mM)
In vivo	1% CMC Na	28 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	22.38 mL	111.88 mL	223.76 mL
0.5 mM	4.48 mL	22.38 mL	44.75 mL
1 mM	2.24 mL	11.19 mL	22.38 mL
5 mM	0.45 mL	2.24 mL	4.48 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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