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Gemcitabine HCl (Gemzar)

Gemcitabine HCl (Gemzar)

Name: Gemcitabine HCl (Gemzar)
SKU: A10423

目录号: A10423

DNA/RNA Synthesis 抑制剂

Product Citations (1)

Gemcitabine HCl (Gemzar) Chemical Structure

CAS NO. 122111-03-9

Gemcitabine HCl (Gemzar)是一种DNA synthesis抑制剂，作用于PANC1，MIAPaCa2，BxPC3和Capan2细胞，通过在癌细胞dna复制过程中取代核酸的一个组成部分，防止肿瘤生长。

库存：现货

规格	价格	数量
25 mg	￥ 210.00
50 mg	￥ 280.00
100 mg	￥ 350.00
200 mg	￥ 420.00

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产品详情

生物活性

靶点信息

DNA synthesis (Capan2 cells)	DNA synthesis (BxPC3 cells)	DNA synthesis (MIAPaCa2 cells)	DNA synthesis (PANC1 cells)
12 nM	18 nM	40 nM	50 nM

溶解度 *

In vitro (25°C)	DMSO	Insoluble
	Water	18 mg/mL (60.06 mM)
	Ethanol	Insoluble
In vivo	Saline	18 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	33.37 mL	166.83 mL	333.67 mL
0.5 mM	6.67 mL	33.37 mL	66.73 mL
1 mM	3.34 mL	16.68 mL	33.37 mL
5 mM	0.67 mL	3.34 mL	6.67 mL

*The above data is based on the productmolecular weight 299.7. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A10423
作用机制	Inhibitor (抑制剂)
M. Wt	299.7
Formula	C9H11F2N3O4.HCI
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	122111-03-9
SMILES	C1=CN(C(=O)N=C1N)[C@H]2C([C@@H]([C@H](O2)CO)O)(F)F.Cl