Gemcitabine
吉西他滨（LY 188011）是一种DNA合成抑制剂，能够抑制BxPC-3、Mia Paca-2、PANC-1、PL-45和AsPC-1细胞的生长，其半抑制浓度（IC50）分别为37.6、42.9、92.7、89.3和131.4纳摩尔（nM）。
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重要通知：仅供研究使用。我们不向患者销售。
顾客使用 Adooq 产品发表的高质量科研文献
Adooq用户使用Gemcitabine发表的3篇文献
生物活性
| Discription | Gemcitabine (LY 188011) is a DNA synthesis inhibitor which inhibits the growth of BxPC-3, Mia Paca-2, PANC-1, PL-45 and AsPC-1 cells with IC50s of 37.6, 42.9, 92.7, 89.3 and 131.4 nM, respectively. | |||||
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| Cell Research |
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产品信息
| 目录号 | A11434 |
|---|---|
| 分子式 | C9H11F2N3O4 |
| 分子量 | 263.2 |
| CAS号 | 95058-81-4 |
| SMILES | O=C1N(C=CC(N)=N1)[C@H]2C(F)([C@@H]([C@H](O2)CO)O)F |
| 其他名称 | LY 188011, LY188011, LY-188011 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro (25°C) | DMSO | 47 mg/mL (178.56 mM) | |
| Water | Warmed: 47 mg/mL (178.56 mM) | ||
| Ethanol | Insoluble | ||
| In vivo | water (warmed) | 49 mg/mL | |
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 37.99 mL | 189.97 mL | 379.94 mL |
| 0.5 mM | 7.6 mL | 37.99 mL | 75.99 mL |
| 1 mM | 3.8 mL | 19 mL | 37.99 mL |
| 5 mM | 0.76 mL | 3.8 mL | 7.6 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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| 购买 95058-81-4 | 95058-81-4 供应商 | 95058-81-4 花费 | 95058-81-4 生产商 | 订购 95058-81-4 | 95058-81-4 代理商