Genistein
目录号: A10425
EGFR 抑制剂
Genistein，一种大豆异黄酮，是一种多重酪氨酸激酶（例如 EGFR）抑制剂，主要通过改变凋亡、细胞周期、血管生成并抑制转移，作为针对不同类型癌症的化疗药物。
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生物活性
| Discription | Genistein, a soy isoflavone, is a multiple tyrosine kinases (e.g., EGFR) inhibitor which acts as a chemotherapeutic agent against different types of cancer, mainly by altering apoptosis, the cell cycle, and angiogenesis and inhibiting metastasis. | |||||
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产品信息
| 目录号 | A10425 |
|---|---|
| 分子式 | C15H10O5 |
| 分子量 | 270.24 |
| CAS号 | 446-72-0 |
| SMILES | OC1=C2C(OC=C(C3=CC=C(O)C=C3)C2=O)=CC(O)=C1 |
| 其他名称 | NPI 031L |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | 50 mg/mL (185.02 mM) | |
| Water | Insoluble | ||
| Ethanol | 2 mg/mL (7.4 mM) | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 37 mL | 185.02 mL | 370.04 mL |
| 0.5 mM | 7.4 mL | 37 mL | 74.01 mL |
| 1 mM | 3.7 mL | 18.5 mL | 37 mL |
| 5 mM | 0.74 mL | 3.7 mL | 7.4 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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| 购买 446-72-0 | 446-72-0 供应商 | 446-72-0 花费 | 446-72-0 生产商 | 订购 446-72-0 | 446-72-0 代理商