Signaling Pathway
| Discription | GGTI298 Trifluoroacetate is a CAAZ peptidomimetic geranylgeranyltransferase I (GGTase I) inhibitor, which can inhibit Rap1A with IC50 of 3 μM; little effect on Ha-Ras with IC50 of >20 μM. |
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| 目录号 | A16560 |
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| 分子式 | C29H34F3N3O5S |
| 分子量 | 593.66 |
| CAS号 | 1217457-86-7 |
| SMILES | CC(C)C[C@@H](C(OC)=O)NC(C1=CC=C(NC[C@@H](N)CS)C=C1C2=C3C=CC=CC3=CC=C2)=O.O=C(O)C(F)(F)F |
| 其他名称 | GGTI 298, GGTI-298 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
| In vitro | DMSO | 87 mg/mL (146.54 mM) | |
| Water | Insoluble | ||
| Ethanol | 87 mg/mL (146.54 mM) | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 16.84 mL | 84.22 mL | 168.45 mL |
| 0.5 mM | 3.37 mL | 16.84 mL | 33.69 mL |
| 1 mM | 1.68 mL | 8.42 mL | 16.84 mL |
| 5 mM | 0.34 mL | 1.68 mL | 3.37 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
