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Gilteritinib (ASP2215)

目录号: A14411
FLT3/Axl 抑制剂
Gilteritinib 是一种强效的 FLT3/AXL 抑制剂,对带有 FLT3-ITD 和/或 FLT3-D835 突变的 AML 显示出强大的抗白血病活性。
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规格 价格 库存 数量
1mg
¥175.00
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2mg
¥315.00
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5mg
¥525.00
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10mg
¥805.00
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25mg
¥1,330.00
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50mg
¥1,995.00
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100mg
¥3,150.00
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500mg
¥7,385.00
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1g
¥9,975.00
现货
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重要通知:仅供研究使用。我们不向患者销售。

顾客使用 Adooq 产品发表的高质量科研文献
Adooq用户使用Gilteritinib (ASP2215)发表的1篇文献
  • Mohammad Azhar, .et al. , Blood Adv, 2022, Aug 31 PMID: 36044389
  • 生物活性
    Discription Gilteritinib is a potent FLT3/AXL inhibitor, which showed potent antileukemic activity against AML with either or both FLT3-ITD and FLT3-D835 mutations.
    Cell Research
    Cell Line Type Value Description References
    产品信息
    目录号 A14411
    分子式 C29H44N8O3
    分子量 552.71
    CAS号 1254053-43-4
    SMILES CCC1=NC(=C(N=C1NC2CCOCC2)NC3=CC(=C(C=C3)N4CCC(CC4)N5CCN(CC5)C)OC)C(=O)N
    其他名称 ASP2215, ASP-2215, ASP 2215
    储存条件

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    溶解性数据
    In vitro DMSO 90 mg/mL (162.83 mM)
    Water Insoluble
    Ethanol 77 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 18.09 mL 90.46 mL 180.93 mL
    0.5 mM 3.62 mL 18.09 mL 36.19 mL
    1 mM 1.81 mL 9.05 mL 18.09 mL
    5 mM 0.36 mL 1.81 mL 3.62 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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