Glecaprevir
目录号: A16948
HCV NS3/4A protease inhibitor
Glecaprevir,也被称为 ABT-493 和 A-1282576,是一种新型的 HCV NS3/4A 蛋白酶抑制剂,其 IC50 值在 3.5 到 11.3 nM 范围内。
Discription | Glecaprevir, also known as ABT-493 and A-1282576, is a novel HCV NS3/4A protease inhibitor, with IC50 values ranging from 3.5 to 11.3 nM. | |||||
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Cell Research |
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目录号 | A16948 |
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分子式 | C38H46F4N6O9S |
分子量 | 838.87 |
CAS号 | 1365970-03-1 |
SMILES | O=C([C@H]1N(C2)C([C@H](C(C)(C)C)NC(O[C@@](CCC3)([H])[C@]3([H])OC/C=C/C(F)(F)C4=NC5=CC=CC=C5N=C4O[C@]2([H])C1)=O)=O)N[C@@]6(C(NS(=O)(C7(C)CC7)=O)=O)[C@H](C(F)F)C6 |
其他名称 | ABT-493, ABT493, ABT 493, A-1282576, A1282576, A 1282576 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 99 mg/mL (118.01 mM) | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 11.92 mL | 59.6 mL | 119.21 mL |
0.5 mM | 2.38 mL | 11.92 mL | 23.84 mL |
1 mM | 1.19 mL | 5.96 mL | 11.92 mL |
5 mM | 0.24 mL | 1.19 mL | 2.38 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2