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(Glu2)-TRH

目录号: A23175
(Glu2)-TRH,一种代谢稳定的促甲状腺激素释放激素(TRH)类似物,是小鼠大脑中TRH胆碱能效应的负调节剂。(Glu2)-TRH 显著减弱了TRH诱导的海马区细胞外乙酰胆碱释放。(Glu2)-TRH 不被甲状腺素释放酶代谢。(Glu2)-TRH 在中枢神经系统(CNS)中表现出神经保护、抗抑郁和抗惊厥的作用。
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5mg
¥455.00
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10mg
¥840.00
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生物活性
Discription (Glu2)-TRH, a metabolically stable analogue of Thyrotropin-releasing hormone (TRH), is a negative modulator for the cholinergic effect of TRH in the mouse brain. (Glu2)-TRH significantly attenuates TRH-induced hippocampal extracellular acetylcholine release. (Glu2)-TRH is not metabolized by thyroliberinase. (Glu2)-TRH manifests neuroprotective, antidepressant, anticonvulsant in the CNS.
产品信息
目录号 A23175
分子式 C15H22N4O6
分子量 354.36
CAS号 85541-78-2
Sequence shortening Glp-EP-NH2
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