Glumetinib (SCC-244)

Name: Glumetinib (SCC-244)
SKU: A18328

目录号: A18328

c-Met inhibitor

Glumetinib (SCC-244) Chemical Structure

CAS NO. 1642581-63-2

Glumetinib (SCC244) is a potent and highly selective c-Met kinase inhibitor with an IC50 of 0.42 nM. Glumetinib shows antitumor activity and a superior safety margin.

库存：现货

规格	价格	数量
5 mg	￥ 910.00
10 mg	￥ 1,400.00
50 mg	￥ 3,500.00
100 mg	￥ 5,600.00

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生物活性

Glumetinib (SCC244) is a potent and highly selective c-Met kinase inhibitor with an IC50 of 0.42 nM. Glumetinib shows antitumor activity and a superior safety margin.

溶解度 *

In vitro	DMSO	10 mg/mL (21.76 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	21.76 mL	108.82 mL	217.63 mL
0.5 mM	4.35 mL	21.76 mL	43.53 mL
1 mM	2.18 mL	10.88 mL	21.76 mL
5 mM	0.44 mL	2.18 mL	4.35 mL

*The above data is based on the productmolecular weight 459.488. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A18328
作用机制	Inhibitor (抑制剂)
M. Wt	459.488
Formula	C21H17N9O2S
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	1642581-63-2
Synonyms	SCC244, SCC 244
SMILES	O=S(N1N=CC2=NC=C(C3=CN(C)N=C3)C=C21)(C4=CN=C5C=CC(C6=CN(C)N=C6)=CN54)=O