GLX351322
目录号: A20327
Nox4 inhibitor
GLX351322 是一种 NADPH 氧化酶 4(Nox4)的抑制剂,能够抑制 NOX4 过表达细胞产生的过氧化氢,其 IC50 为 5 微摩尔。
Discription | GLX351322 is an inhibitor of NADPH oxidase 4 (Nox4), and inhibits hydrogen peroxide production from NOX4-overexpressing cells with an IC50 of 5 μM. |
---|
目录号 | A20327 |
---|---|
分子式 | C21H25N3O5S |
分子量 | 431.51 |
CAS号 | 835598-94-2 |
SMILES | O=C(OCC)C1=C(SC2=C1CCC2)NC(CN3CCN(CC3)C(C4=CC=CO4)=O)=O |
其他名称 | GLX 351322, GLX-351322 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 19 mg/mL (44.02 mM) | |
Water | Insoluble | ||
Ethanol | 4 mg/mL (9.26 mM) | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 23.17 mL | 115.87 mL | 231.74 mL |
0.5 mM | 4.63 mL | 23.17 mL | 46.35 mL |
1 mM | 2.32 mL | 11.59 mL | 23.17 mL |
5 mM | 0.46 mL | 2.32 mL | 4.63 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2