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GMB475

目录号: A22279
BCR-ABL1 tyrosine kinase degrader
GMB-475 是一种基于 PROTACBCR-ABL1 酪氨酸激酶 降解剂,能够克服依赖 BCR-ABL1 的药物抗性。
Grouped product items
规格 价格 库存 数量
1mg
¥560.00
现货
5mg
¥910.00
现货
10mg
¥1,505.00
现货
25mg
¥2,730.00
现货
50mg
¥4,060.00
现货
100mg
¥7,140.00
现货
500mg
¥16,975.00
现货
10mM * 1mL in DMSO
¥1,960.00
现货
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生物活性
Discription GMB-475 is a degrader of BCR-ABL1 tyrosine kinase based on PROTAC, overcoming BCR-ABL1-dependent drug resistance.
产品信息
目录号 A22279
分子式 C43H46F3N7O7S
分子量 861.93
CAS号 2490599-18-1
SMILES FC(F)(F)OC1=CC=C(NC2=CC(C3=CC=C(OCCOCC(N[C@H](C(C)(C)C)C(N4[C@H](C(NCC5=CC=C(C6=C(C)N=CS6)C=C5)=O)CC(O)C4)=O)=O)C=C3)=NC=N2)C=C1
储存条件

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Molecular Weight

Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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