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GMB475

GMB475

Name: GMB475
SKU: A22279

目录号: A22279

BCR-ABL1 tyrosine kinase degrader

GMB475 Chemical Structure

CAS NO. 2490599-18-1

GMB-475 is a degrader of BCR-ABL1 tyrosine kinase based on PROTAC, overcoming BCR-ABL1-dependent drug resistance.

库存：现货

规格	价格	数量
10 mg	￥ 1,575.00
25 mg	￥ 3,150.00
50 mg	￥ 5,425.00
100 mg	￥ 9,275.00

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产品仅用于科学研究，不针对患者销售，望谅解.

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生物活性

GMB-475 is a degrader of BCR-ABL1 tyrosine kinase based on PROTAC, overcoming BCR-ABL1-dependent drug resistance.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	11.6 mL	58.01 mL	116.02 mL
0.5 mM	2.32 mL	11.6 mL	23.2 mL
1 mM	1.16 mL	5.8 mL	11.6 mL
5 mM	0.23 mL	1.16 mL	2.32 mL

*The above data is based on the productmolecular weight 861.93. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A22279
M. Wt	861.93
Formula	C43H46F3N7O7S
Solubility	DMSO
Purity	>98%
Storage	at -20°C 2 years
CAS No.	2490599-18-1
SMILES	FC(F)(F)OC1=CC=C(NC2=CC(C3=CC=C(OCCOCC(N[C@H](C(C)(C)C)C(N4[C@H](C(NCC5=CC=C(C6=C(C)N=CS6)C=C5)=O)CC(O)C4)=O)=O)C=C3)=NC=N2)C=C1