GNE-049
目录号: A20206
CBP 抑制剂
GNE-049 是一种高效且选择性的 CBP 抑制剂,在 TR-FRET 检测中的 IC50 为 1.1 nM。GNE-049 还能抑制 BRET 和 BRD4(1),其 IC50 分别为 12 nM 和 4200 nM。
Discription | GNE-049 is a highly potent and selective CBP inhibitor with an IC50 of 1.1 nM in TR-FRET assay. GNE-049 also inhibits BRET and BRD4(1) with IC50s of 12 nM and 4200 nM, respectively. | |||||
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Cell Research |
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目录号 | A20206 |
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分子式 | C27H32F2N6O2 |
分子量 | 510.58 |
CAS号 | 1936421-41-8 |
SMILES | CC(N1CCC(N(C2CCOCC2)N=C3N4CCCC5=C4C=C(C(F)F)C(C6=CN(C)N=C6)=C5)=C3C1)=O |
其他名称 | GNE049, GNE 049 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2