GNE 477

目录号: A14114

PI3K/mTOR 抑制剂

GNE 477

GNE 477 Chemical Structure

CAS NO. 1032754-81-6

GNE-477是一种有效的PI3K/mTOR双重抑制剂,PI3Kα的IC50为4 nM,Kiapp为mTOR的IC50为21 nM。

库存: 现货

规格 价格 数量
2 mg
¥ 630.00
5 mg
¥ 1,190.00
10 mg
¥ 2,030.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

GNE-477是一种有效的PI3K/mTOR双重抑制剂,PI3Kα的IC50为4 nM,Kiapp为mTOR的IC50为21 nM。
In vitro DMSO 24 mg/mL (47.56 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.82 mL 99.08 mL 198.16 mL
0.5 mM 3.96 mL 19.82 mL 39.63 mL
1 mM 1.98 mL 9.91 mL 19.82 mL
5 mM 0.4 mL 1.98 mL 3.96 mL

*The above data is based on the productmolecular weight 504.64. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A14114
作用机制 Inhibitor (抑制剂)
M. Wt 504.64
Formula C21H28N8O3S2
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 1032754-81-6
Synonyms GNE-477,GNE477
SMILES CC1=C(SC2=C1N=C(N=C2N3CCOCC3)C4=CN=C(N=C4)N)CN5CCN(CC5)S(=O)(=O)C

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