GNE-493
目录号: A14432
Dual Pan PI3k/mTOR 抑制剂
GNE-493 是一种效力强大、选择性高、可口服的全泛PI3激酶和双重全泛PI3激酶/mTOR抑制剂,具有潜在的抗癌活性。
Discription | GNE-493 is potent, selective, and orally available pan-PI3-kinase and dual pan-PI3-kinase/mTOR inhibitor with potential anticancer activity. | |||||
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Targets |
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Cell Research |
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目录号 | A14432 |
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分子式 | C17H20N6O2S |
分子量 | 372.44 |
CAS号 | 1033735-94-2 |
SMILES | CC(C)(C1=CC2=C(S1)C(=NC(=N2)C3=CN=C(N=C3)N)N4CCOCC4)O |
其他名称 | GNE493, GNE 493 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 63 mg/mL (169.15 mM) | |
Water | Insoluble | ||
Ethanol | 1 mg/mL | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 26.85 mL | 134.25 mL | 268.5 mL |
0.5 mM | 5.37 mL | 26.85 mL | 53.7 mL |
1 mM | 2.68 mL | 13.42 mL | 26.85 mL |
5 mM | 0.54 mL | 2.68 mL | 5.37 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2