GNE 5729
目录号: A20295
NMDAR modulator
GNE 5729 是一种能穿透血脑屏障的 NMDAR 正向异构调节剂,对 GluN2A 的 EC50 为 37 nM,对 GluN2C 和 GluN2D 分别为 4.7 和 9.5 μM。
Discription | GNE 5729 is a brain permeable positive allosteric modulator of NMDAR, with an EC50 of 37 nM for GluN2A, 4.7 and 9.5 μM for GluN2C and GluN2D, respectively. | |||||
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Cell Research |
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目录号 | A20295 |
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分子式 | C17H10Cl2F3N5O |
分子量 | 428.2 |
CAS号 | 2026635-66-3 |
SMILES | ClC1=C([C@H]2[C@H](C#N)C2)N3C(C=C1)=NC(CN4N=C(C(F)(F)F)C=C4Cl)=CC3=O |
其他名称 | GNE-5729; GNE5729 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2