GNE-616

Name: GNE-616
SKU: A19046
Price: 6440 CNY
Rating: 5 (288 reviews)

目录号: A19046

Nav1.7 inhibitor

GNE-616 是一种高效、代谢稳定、口服生物利用度高且亚型选择性的 Nav1.7 抑制剂（对 hNav1.7 的 Ki 为 0.79 nM，Kd 为 0.38 nM），用于治疗慢性疼痛。

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规格	价格	库存
5mg	¥6,440.00	现货
10mg	¥10,360.00	现货
25mg	¥21,560.00	现货
50mg	¥28,140.00	现货
100mg	¥39,760.00	现货
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Data Sheet

SDS

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生物活性

Discription

GNE-616 is a highly potent, metabolically stable, orally bioavailable, and subtype selective Nav1.7 inhibitor (Ki of 0.79 nM and Kd of 0.38 nM for hNav1.7) for the treatment of chronic pain.

Targets

Target	Value

产品信息

目录号	A19046
分子式	C24H23F4N5O3S
分子量	537.53
CAS号	2349371-81-7
SMILES	O=S(C1=C(F)C=C2[C@@H](N3[C@@H](C4=NC=CC=C4)C[C@@H](C(F)(F)F)CC3)CCOC2=C1)(NC5=NC=NC=C5)=O
其他名称	GNE 616, GNE616
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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