GNE-617
目录号: A13318
NAMPT 抑制剂
GNE-617 是一种强效的烟酰胺磷酸核糖转移酶（NAMPT）抑制剂，其半抑制浓度（IC50）值为5nM。
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生物活性
| Discription | GNE-617 is a potent nicotinamide phosphoribosyltransferase (NAMPT) inhibitor with IC50 value of 5nM. | |||||
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| Cell Research |
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产品信息
| 目录号 | A13318 |
|---|---|
| 分子式 | C21H15F2N3O3S |
| 分子量 | 427.42 |
| CAS号 | 1362154-70-8 |
| SMILES | FC1=CC(S(C2=CC=C(C=C2)CNC(C(C=C3)=CN4C3=NC=C4)=O)(=O)=O)=CC(F)=C1 |
| 其他名称 | GNE 617, GNE617 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | 37 mg/mL (86.56 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 23.4 mL | 116.98 mL | 233.96 mL |
| 0.5 mM | 4.68 mL | 23.4 mL | 46.79 mL |
| 1 mM | 2.34 mL | 11.7 mL | 23.4 mL |
| 5 mM | 0.47 mL | 2.34 mL | 4.68 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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