微信关注
Total item
Cart Subtotal
￥ 0.00 产品详情
GNE-7915是一种富含亮氨酸重复激酶2（LRRK2）的血脑屏障（BBB）渗透性小分子抑制剂。
靶点信息
| LRRK2 | LRRK2 | |||
| 1 nM(Ki) | 9 nM |
| In vitro (25°C) | DMSO | Warmed: 21 mg/mL (47.36 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
| In vivo | 5% DMSO+30% PEG 300+5% Tween 80+ddH2O | 2.9 mg/mL | |
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 22.55 mL | 112.77 mL | 225.53 mL |
| 0.5 mM | 4.51 mL | 22.55 mL | 45.11 mL |
| 1 mM | 2.26 mL | 11.28 mL | 22.55 mL |
| 5 mM | 0.45 mL | 2.26 mL | 4.51 mL |
*The above data is based on the productmolecular weight 443.395. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A13748 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 443.395 |
| Formula | C19H21F4N5O3 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 1351761-44-8 |
| Synonyms | GNE7915, GMS 7915 |
| SMILES | CCNC1=NC(=NC=C1C(F)(F)F)NC2=C(C=C(C(=C2)F)C(=O)N3CCOCC3)OC |
产品标签
Product Questions
Product Questions
No Questions
Keywords:购买 GNE-7915 | GNE-7915 供应商 | 订购 GNE-7915 | GNE-7915 价格 | GNE-7915 生产商 | 订单 GNE-7915 | GNE-7915 代理商 | 购买 1351761-44-8| 1351761-44-8 供应商 | 订购 1351761-44-8 | 1351761-44-8 价格 | 1351761-44-8 生产商 | 订单 1351761-44-8 | 1351761-44-8 代理商|buy GNE-7915 | GNE-7915 Supplier | purchase GNE-7915 | GNE-7915 cost | GNE-7915 manufacturer | order GNE-7915 | GNE-7915 distributor | buy 1351761-44-8| 1351761-44-8 Supplier | purchase 1351761-44-8 | 1351761-44-8 cost | 1351761-44-8 manufacturer | order 1351761-44-8 | 1351761-44-8 distributor