GNE 9605

Name: GNE 9605
SKU: A14149
Price: 210 CNY
Rating: 5 (1 reviews)

目录号: A14149

LRRK2 抑制剂

1 篇发表文献

GNE-9605 是一种高效且选择性的富含亮氨酸重复激酶 2（LRRK2）抑制剂，其 Ki 和 IC50 分别为 2 nM 和 19 nM。

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Grouped product items
规格	价格	库存
2mg	¥210.00	现货
5mg	¥350.00	现货
10mg	¥560.00	现货
25mg	¥1,085.00	现货
50mg	¥1,785.00	现货
100mg	¥2,695.00	现货
*10mM 1mL in DMSO**	¥385.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用GNE 9605发表的1篇文献

Vijaya Bharti, .et al. , Cell Rep, 2022, Dec 20;41(12):111826 PMID: 36543138

生物活性

Discription

GNE-9605 is a highly potent and selective leucine-rich repeat kinase 2 (LRRK2) inhibitor with Ki and IC50 of 2 nM and 19 nM, respectively.

Targets

Target	Value

产品信息

目录号	A14149
分子式	C17H20ClF4N7O
分子量	449.83
CAS号	1536200-31-3
SMILES	CNC1=NC(=NC=C1C(F)(F)F)NC2=C(N(N=C2)[C@H]3CCN(C[C@@H]3F)C4COC4)Cl
其他名称	GNE-9605,GNE9605
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	84 mg/mL (186.73 mM)
	Water	Insoluble
	Ethanol	Warmed: 11 mg/mL (24.45 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	22.23 mL	111.15 mL	222.31 mL
0.5 mM	4.45 mL	22.23 mL	44.46 mL
1 mM	2.22 mL	11.12 mL	22.23 mL
5 mM	0.44 mL	2.22 mL	4.45 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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