GNF-7

Name: GNF-7
SKU: A15887
Price: 210 CNY
Rating: 5 (288 reviews)

目录号: A15887

Bcr-Abl 抑制剂

GNF-7 是一种强效的 II 型激酶 Bcr-Abl 抑制剂，其 IC50 分别为 M351T (<5 nM)、T315I (61 nM)、E255V (122 nM)、G250E (136 nM) 和 c-Abl (133 nM)。

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Grouped product items
规格	价格	库存
1mg	¥210.00	现货
5mg	¥560.00	现货
10mg	¥980.00	现货
25mg	¥2,030.00	现货
50mg	¥3,185.00	现货
100mg	¥5,110.00	现货
*10mM 1mL in DMSO**	¥630.00	现货
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Data Sheet

SDS

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生物活性

Discription

GNF-7 is a potent type-II kinase Bcr-Abl inhibitor with IC50 of <5 nM, 61 nM, 122 nM, 136 nM, and 133 nM for M351T, T315I, E255 V, G250E, and c-Abl, respectively.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A15887
分子式	C28H24F3N7O2
分子量	547.53
CAS号	839706-07-9
SMILES	O=C(NC1=CC=C(C)C(N2CC3=CN=C(NC4=CC=C(C)N=C4)N=C3N(C)C2=O)=C1)C5=CC=CC(C(F)(F)F)=C5
其他名称	GNF7, GNF 7
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	17 mg/mL (31.04 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	18.26 mL	91.32 mL	182.64 mL
0.5 mM	3.65 mL	18.26 mL	36.53 mL
1 mM	1.83 mL	9.13 mL	18.26 mL
5 mM	0.37 mL	1.83 mL	3.65 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

Calculate Reset

* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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